Ortelius was demonstrated at the AAG conference in Las Vegas in mid March and looks promising. It’s billed as an affordable middle-way between Adobe Illustrator + MaPublisher and ArcGIS and it works on Macs, which ArcGIS does not. It’s a graphics design package that can import shapefiles and purports knowing object topology. It also has an integrated database so you can view and edit map object attributes. Map projections are supported and the package comes with pre-loaded map files to get you started.
Ortelius is currently under development and version 1.0 will be available in the first quarter of 2009. The intention is to release standard and “pro” versions with a starting price of $79. Thanks to Martin for this tip.